abstract：:Genome-wide association studies have revealed several gene variants associated with obesity; however, only a few studies have further investigated their association with metabolic syndrome. We performed a study of eleven variants in/near genes TMEM18, SH2B1, KCTD15, PCSK1, BDNF, SEC16B, MC4R, and FTO in Czech adolesce...

journal_title：Folia biologica

authors： Dušátková L,Zamrazilová H,Sedláčková B,Včelák J,Hlavatý P,Aldhoon Hainerová I,Korenková V,Bradnová O,Bendlová B,Kunešová M,Hainer V

更新日期：2013-01-01 00:00:00

abstract：:Using the protein-protein docking program, this study investigates the relationship between TRAF2 and its related proteins and the diversity within the 3D structures of TRAF2s. TRAF2 exists in monomer, trimer, and hexamer forms and it can combine with a number of prote...

journal_title：Folia biologica

authors： Zeng F,Wu Q,Guo E,Guo H,Wang H,Shan J,Wei R

更新日期：2012-01-01 00:00:00

abstract：:Mating types are expressed in ciliates for the duration of the mature period of their clonal cycle. During cell conjugation the reciprocal fertilization of complementary mating types takes place. Models of mating type determination in the Paramecium aurelia species complex based on classical genetics are reviewed incl...

journal_title：Folia biologica

authors： Sawka N

更新日期：2012-01-01 00:00:00

abstract：:The aim of the research was to determine the concentration of total protein and its fractions as well as the concentration of selected mineral components in the blood serum of male broiler chickens Cobb 500 fed diets with different cellulose content. Blood samples were collected for examination from the birds' pterygo...

journal_title：Folia biologica

authors： Bogusławska-Tryk M,Szymeczko R,Piotrowska A

更新日期：2012-01-01 00:00:00

abstract：UNLABELLED:The most frequent cause of ischaemic heart disease is coronary arteriosclerosis. This study was aimed at assessing gene expression of TNFA and its two receptors (TNFR1, TNFR2), as well as determining coronary artery calcium score (CACS) in the context of occu...

journal_title：Folia biologica

authors： Dabek J,Swiderski R,Głogowska-Ligus J,Pysz P

更新日期：2012-01-01 00:00:00

abstract：:Epigenetic changes are considered to be a frequent event during tumour development. Hypermethylation of promoter CpG islands represents an alternative mechanism for inactivation of tumour suppressor genes, DNA repair genes, cell cycle regulators and transcription facto...

journal_title：Folia biologica

authors： Chmelařová M,Křepinská E,Spaček J,Laco J,Nekvindová J,Palička V

更新日期：2012-01-01 00:00:00

abstract：:We have studied a rapid cultivation method for human mesenchymal stromal cells based on CellGroTM medium and human serum, supplemented with insulin, ascorbic acid, dexamethasone, epidermal growth factor, platelet-derived growth factor BB, macrophage colony-stimulating ...

journal_title：Folia biologica

authors： Stehlík D,Pytlík R,Rychtrmocová H,Kideryová L,Veselá R,Kopečný Z,Trč T,Trněný M

更新日期：2012-01-01 00:00:00

abstract：:We examined the sexual development and insemination capability of boars representing five breeds used at Polish sow insemination stations. The speed of attaining full breeding maturity by the boars and their insemination usefulness was assessed based on the results of experiments analysing age-related changes in the p...

journal_title：Folia biologica

authors： Banaszewska D,Kondracki S

更新日期：2012-01-01 00:00:00

abstract：:In the mammalian ovary, matrix metalloproteinase-2 (MMP-2) is thought to be involved in the regulated turnover of the extracellular matrix during the process of follicle development, ovulation and regression. Information concerning the role of MMP-2 in the chicken ovary is scarce. The present investigation was underta...

journal_title：Folia biologica

authors： Leśniak A,Hrabia A

更新日期：2012-01-01 00:00:00

abstract：:Cellular senescence is a condition of longlasting proliferation arrest, induced in cells in response to various stressors. These stressors include telomere shortening and/or dysfunction, DNA damage, and oncogene signalling. Epithelial and mesenchymal cells and also tumour cells derived from these tissues are more resi...

journal_title：Folia biologica

authors： Vávrová J,Rezáčová M

更新日期：2011-01-01 00:00:00

abstract：:Shock waves, pressure waves manifested as a sharp increase in positive pressure followed by a decrease and the negative part of the wave, are not only used to treat concrements in medicine. Recently, research has been focused on the possibility of their use for damagin...

journal_title：Folia biologica

authors： Beneš J,Poučková P,Zeman J,Zadinová M,Sunka P,Lukeš P,Kolářová H

更新日期：2011-01-01 00:00:00

abstract：:We have shown previously that stubby worms Allolobophora chlorotica are sensitive to environmental stress, including metal-polluted soil. In order to discern the mechanisms of this sensitivity, adult (clitellate) Al. chlorotica were exposed in the laboratory to soil samples soaked with water (control) or Ni (1 and 2 m...

journal_title：Folia biologica

authors： Podolak A,Piotrowska E,Klimek M,Klimek BA,Kruk J,Plytycz B

更新日期：2011-01-01 00:00:00

abstract：:The experiment was carried out on 10 clinically healthy Polish-Friesian var. Black-and-White cow calves, during the first seven days of postnatal life. The results indicate that renal removal of potassium depends primarily on the quantity reabsorbed in the tubules, whereas clearance of the electrolyte, due to stable l...

journal_title：Folia biologica

authors： Dratwa-Chałupnik A,Ozgo M,Herosimczyk A,Lepczyński A,Michałek K,Skrzypczak W

更新日期：2011-01-01 00:00:00

abstract：:The genetic basis for atherosclerosis development and progression is poorly characterized. We aimed to assess the relationship between endothelial nitric oxide synthase (ENOS) 894 G/T, haem oxygenase-1 (HO1) dinucleotide-length promoter polymorphisms and coronary artery atherosclerotic invol vement and its changes dur...

journal_title：Folia biologica

authors： Král A,Kovárník T,Králík L,Skalická H,Horák J,Mintz GS,Uhrová J,Sonka M,Wahle A,Downe R,Aschermann M,Martásek P,Linhart A

更新日期：2011-01-01 00:00:00

abstract：:The mRNA differential display technique was performed to investigate the differences of gene expression in the longissimus muscle tissues from Meishan and Large White pigs. One novel gene that was differentially expressed was identified through semi-quantitative RT-PCR and the cDNA complete sequence was then obtained ...

journal_title：Folia biologica

authors： Jiugang Z,Jing L,Yonggang L

更新日期：2011-01-01 00:00:00

abstract：:Reasons for the increased prevalence of allergies observed in recent decades remain elusive. Here, we used a murine model to investigate the effect of nutrition on ovalbumin-induced allergic peritonitis. Compared to the organs of mice kept on a standard diet, mice exposed to a low quality diet during the growth period...

journal_title：Folia biologica

authors： Chadzinska M,Broniek B,Radwan J

更新日期：2011-01-01 00:00:00

abstract：:The aim of this study was to verify whether the separation and elimination of the apoptotic fraction in rabbit semen using a MACS technique may improve sperm fertility potential and consequently rabbit kindling rate. Semen samples from 25 New Zealand White (NZW) rabbit males were collected using an artificial vagina a...

journal_title：Folia biologica

authors： Vasicek J,Parkanyi V,Ondruska L,Makarevich A,Chrenek P

更新日期：2011-01-01 00:00:00

abstract：:Oxazaphosphorines are a class of DNA alkylating agents. The aim of the present study was to compare the possible influence of three new generation oxazaphosphorines, D-17272 (mafosfamide cyclohexylamine salt), D-18864 (4-hydro-peroxy-cyclophosphamide), and D-19575 (glufosfamide, beta-D-glucose-isophosphoramide mustard...

journal_title：Folia biologica

authors： Mazur L,Opydo-Chanek M,Stojak M,Baran J,Niemeyer U

更新日期：2010-01-01 00:00:00

abstract：:Disturbed trophoblast turnover, a key process in placental physiology, may lead to a number of pregnancy-associated pathologies. This study examines PCNA expression and describes and quantifies morphological changes during trophoblast turnover in preterm placentas and term placentas complicated by IUGR. The number ofC...

journal_title：Folia biologica

authors： Zadrozna M,Nowak B,Marcinek A,Duc J

更新日期：2010-01-01 00:00:00

abstract：:We have studied the number of endothelial precursor cells in eighteen patients undergoing allogeneic haematopoietic stem cell transplantation. Endothelial precursor cells were evaluated by colony-forming assay and compared to healthy controls. Patients undergoing allogeneic haematopoietic stem cell transplantation had...

journal_title：Folia biologica

authors： Pytlík R,Kideryová L,Benesová K,Cechová H,Veselá R,Rychtrmocová H,Trnený M

更新日期：2010-01-01 00:00:00

abstract：:In the recent years, iodine was associated to the development of apoptosis in thyroid diseases. The aim of the present study is to determine the expression of pro-apoptotic and anti-apoptotic proteins, Bax and Bcl-2, in a Wistar rat experimental model of thyroiditis induced by administration of different doses of pota...

journal_title：Folia biologica

authors： Marković L,Todorović J,Stanković G,Radojević S,Gvozdenović E,Aritonović J,Stupar N,Maglić GV

更新日期：2010-01-01 00:00:00

abstract：:The karyotypes of the lesser Egyptian jerboa Jaculus jaculus and the greater Egyptian jerboa Jaculus orientalis from Tunisia are described and compared with available data particularly from Egypt. The species examined have a similar karyotype consisting of 2n = 48 chromosomes and a fundamental number of autosomes (NFa...

journal_title：Folia biologica

authors： Ben Faleh A,Ben Othmen A,Said K,Granjon L

更新日期：2010-01-01 00:00:00

abstract：:Response surface methodology was used to evaluate the effect of main variables such as concentration of galactose, yeast extract and wheat bran on alpha-galactosidase production from Aspergillus parasiticus MTCC-2796 under submerged fermentation conditions. A full factorial Central Composite Design was applied to stud...

journal_title：Folia biologica

authors： Shivam K,Mishra SK

更新日期：2010-01-01 00:00:00

abstract：:Reactivation of tumour suppressor genes that have been silenced by promoter methylation is a very attractive molecular target for cancer therapy. The treatment of a squamous cervical cancer cell line, SiHa, with 20 μM curcumin and genistein resulted in demethylation of promoter of the RARβ2 gene and led to the reactiv...

journal_title：Folia biologica

authors： Jha AK,Nikbakht M,Parashar G,Shrivastava A,Capalash N,Kaur J

更新日期：2010-01-01 00:00:00

abstract：:This study was designed to test the role of liver lipases in the degradation of liver triacylglycerols (TAG) and to determine the effect of dietary induced TAG accumulation in the liver on regulation of their lipolysis. Male Wistar rats were administered high-fat or high-sucrose diet for two weeks. Individual lipases ...

journal_title：Folia biologica

authors： Cahová M,Daňková H,Páleníčková E,Papáčková Z,Kazdová L

更新日期：2010-01-01 00:00:00

abstract：:Haptoglobin is a glycoprotein involved in the acute phase response. Previously we reported that haptoglobin gene expression was up-regulated during dietary restriction in young female rats. The present study aimed at determining whether chronic dietary restriction affects haptoglobin blood levels through changing leve...

journal_title：Folia biologica

authors： Uskoković A,Arambasić J,Bogojević D,Ivanović-Matić S,Mihailović M,Dinić S,Grigorov I

更新日期：2009-01-01 00:00:00

abstract：:Although nuts are typically high in dietary fat, novel studies have shown that regular consumption of these heart-healthy foods might confer a beneficial effect on cardiovascular disease risk. In the present study, we aimed to analyse the effects of pistachio consumption on blood lipids, antioxidant activity, oxidativ...

journal_title：Folia biologica

authors： Alturfan AA,Emekli-Alturfan E,Uslu E

更新日期：2009-01-01 00:00:00

abstract：:A cytogenetic study was conducted on two species of the genus Pimelodus that were collected from the Piquiri river, Paraná, Brazil: Pimelodus paranaensis and Pimelodus heraldoi. Both had a diploid number of 2n=56 chromosomes and a fundamental number (FN) of 104. In P. paranaensis, the karyotype consisted of 22m+22sm+4...

journal_title：Folia biologica

authors： Treco FR,Dias AL

更新日期：2009-01-01 00:00:00

abstract：:Enhanced sialylation of glycoproteins occurs during hypo- and hyperthyroidism. The role of sialic acid (SA) in cell membranes is well-standing, but its role in intracellular structures is still under analysis. We wanted to evaluate the influence of thyroid hormones on the sialylation ratio of intracellular proteins pr...

journal_title：Folia biologica

authors： Nowosadzka E,Szymonik-Lesiuk S,Kurzepa J

更新日期：2009-01-01 00:00:00

abstract：:DNA-dependent protein kinase is a serine/ threonine kinase consisting of a catalytic subunit, p460, and a regulatory subunit called Ku (p80/p70). DNA-dependent protein kinase plays a role in transcription, non-homologous recombination, and DNA repair. Previous data have shown the presence of DNA-dependent protein kina...

journal_title：Folia biologica

authors： Kanungo J

更新日期：2009-01-01 00:00:00

abstract：:Carbamate pesticides generally possess low toxicity for warm-blooded vertebrates, but developmental data are scarce. We have therefore evaluated embryotoxicity of choline esterase inhibitor bendiocarbamate in the chick embryo. The pesticide was dissolved in 5% acetone in distilled water and a volume of 200 microl was ...

journal_title：Folia biologica

authors： Peterovová E,Sedmera D,Mísek I,Lesník F,Luptáková L

更新日期：2009-01-01 00:00:00

abstract：:In the present study 25 specimens of Rhamdia quelen from four different localities were analyzed cytogenetically. All showed a diploid number of 58 chromosomes, with a karyotypic formula of 36m + 16sm + 6st and FN = 116. Metacentric B chromosomes showing inter- and intraindividual variation were observed in all popula...

journal_title：Folia biologica

authors： de Moraes VP,Carneiro Jde S,Dias AL

更新日期：2009-01-01 00:00:00

abstract：:The clinical course of chronic renal diseases and their progression to ESRD is highly variable. The strongest predictors of poor outcome of IgAN involve hypertension, severe proteinuria and elevated serum creatinine level. Different candidate gene polymorphisms have been advocated as possible modulators of the progres...

journal_title：Folia biologica

authors： Maixnerová D,Merta M,Reiterová J,Stekrová J,Rysavá R,Viklický O,Obeidová H,Tesar V

更新日期：2008-01-01 00:00:00

abstract：:The polymorphic inheritance of human drug-metabolizing enzymes, such as those encoded by the GST and CYP systems, has been implicated in both cancer risk and prognostic. In an effort to increase our understanding of the interaction between potential environmental exposure, lifestyle, and genetic factors in the predisp...

journal_title：Folia biologica

authors： Lima MM Jr,Oliveira MN,Granja F,Trindade AC,De Castro Santos LE,Ward LS

更新日期：2008-01-01 00:00:00

abstract：:Differences in microscopic structure of the femur between 1-month-old transgenic rabbits carrying the hFVIII gene and non-transgenic rabbits were investigated. Bone microstructure was evaluated from the point of view of qualitative and quantitative histological characteristics. We identified fibrolamellar bone tissue ...

journal_title：Folia biologica

authors： Martiniaková M,Omelka R,Grosskopf B,Smoláriková V,Bauerová M,Chrenek P

更新日期：2008-01-01 00:00:00

abstract：:Using the protein array method we determined the serum levels of a number of angiogenic factors. We identified serum levels of angiogenin, PDGF and MCP-1 (CCL2 chemokine) in serum of 32 patients with RCC, and 14 healthy volunteers by means of antibody array analysis. The patients were divided into three groups accordi...

journal_title：Folia biologica

authors： Lukesová S,Kopecký O,Vroblová V,Hlávková D,Andrýs C,Morávek P,Cermáková E

更新日期：2008-01-01 00:00:00

abstract：:ACI is the most widely used cell-based surgical procedure for the repair of articular cartilage defects. The method is based on in vitro chondrocyte cultivation. Two different culture conditions, rotating-wall-vessel bioreactor and static culture, were assessed by their effect on the re-differentiation potential of hu...

journal_title：Folia biologica

authors： Barlic A,Kregar-Velikonja N

更新日期：2008-01-01 00:00:00

abstract：:The karyotype and male reproductive system, with special reference to the number of testicular follicles and shape of seminal vesicles, were studied in Dorypteryx domestica (Smithers, 1958) (Psocoptera: Trogiomorpha: Psyllipsocidae). This species displays 2n = 29 (28+X), a single nucleolus connected with one of the la...

journal_title：Folia biologica

authors： Golub NV,Kucerová Z

更新日期：2008-01-01 00:00:00

abstract：:Inducible nitric oxide synthase (iNOS) is one of the enzymes responsible for NO production in neutrophils (PMN) and in peripheral blood mononuclear cells (PBMC). Several studies have demonstrated that iNOS expression is controlled by a wide group of cytokines which achieve their biological effect through, among others...

journal_title：Folia biologica

authors： Jablonska E,Ratajczak W,Jablonski J

更新日期：2008-01-01 00:00:00

abstract：:The random amplified polymorphic DNA (RAPD-PCR) method was used to study the genetic polymorphism of 20 species of the genus Isophya. Each primer amplified a different set of DNA fragments, all oligonucleotides failed to generate any specific diagnostic band that could lead to the identification of Isophya species, an...

journal_title：Folia biologica

authors： Grzywacz B,Warchałowska-Sliwa E

更新日期：2008-01-01 00:00:00